Structured Summary
Abstract
A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.
Chemical Identity
Chemical Information
- Molecular Formula
- C12H15N
- Molecular Weight
- 173.25 g/mol
- CAS Registry No.
- 28289-54-5
- IUPAC Name
- 1-methyl-4-phenyl-3,6-dihydro-2H-pyridine
- InChIKey
- PLRACCBDVIHHLZ-UHFFFAOYSA-N
- SMILES
- CN1CCC(=CC1)C2=CC=CC=C2
- MeSH Unique ID
- D015632
- Source
- PubChem CID 1388
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
2 entry terms
- MPTP
- N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
MeSH Record
Aspects Covered
23 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, radiation effects, standards, supply & distribution, therapeutic use, urine.
MeSH Record
History Note
90
MeSH Record
Previous Indexing
- Pyridines (1966-1989)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Medical Subject Headings (MeSH). 2026. Unique ID D015632. http://id.nlm.nih.gov/mesh/2026/D015632
- 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine. In: Wikipedia. https://en.wikipedia.org/wiki/MPTP
- 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine. In: Wikidata. https://www.wikidata.org/wiki/Q239816
- 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine. In: PubChem Compound. CID 1388. https://pubchem.ncbi.nlm.nih.gov/compound/1388