Chemicals and Drugs

1-Pyrroline-5-Carboxylate Dehydrogenase

An enzyme that catalyzes the oxidation of 1-pyrroline-5-carboxylate to L-GLUTAMATE in the presence of NAD. Defects in the enzyme are the cause of hyperprolinemia II.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the oxidation of 1-pyrroline-5-carboxylate to L-GLUTAMATE in the presence of NAD. Defects in the enzyme are the cause of hyperprolinemia II.

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MeSH Record

Synonyms

13 entry terms
  • Delta(1)-Pyrroline-5-Carboxylate Dehydrogenase
  • GGS Dehydrogenase
  • Glutamic-Gamma-Semialdehyde Dehydrogenase
  • Glutamyl-Gamma-Semialdehyde Dehydrogenase
  • NADP+ Specific 8-Glutamate Semialdehyde Dehydrogenase
  • 1 Pyrroline 5 Carboxylate Dehydrogenase
  • Dehydrogenase, 1-Pyrroline-5-Carboxylate
  • Dehydrogenase, GGS
  • Dehydrogenase, Glutamic-Gamma-Semialdehyde
  • Dehydrogenase, Glutamyl-Gamma-Semialdehyde
  • Glutamic Gamma Semialdehyde Dehydrogenase
  • Glutamyl Gamma Semialdehyde Dehydrogenase
  • NADP+ Specific 8 Glutamate Semialdehyde Dehydrogenase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1981)

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AMA Style

References

  1. National Library of Medicine. 1-Pyrroline-5-Carboxylate Dehydrogenase. Medical Subject Headings (MeSH). 2026. Unique ID D050842. http://id.nlm.nih.gov/mesh/2026/D050842
  2. 1-Pyrroline-5-Carboxylate Dehydrogenase. In: Wikipedia. https://en.wikipedia.org/wiki/1-Pyrroline-5-carboxylate_dehydrogenase
  3. 1-Pyrroline-5-Carboxylate Dehydrogenase. In: Wikidata. https://www.wikidata.org/wiki/Q3380505