Chemicals and Drugs

1,2-Dimethylhydrazine

A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.

Chemical Identity

Chemical Information

Molecular Formula
C2H8N2
Molecular Weight
60.10 g/mol
CAS Registry No.
540-73-8
IUPAC Name
1,2-dimethylhydrazine
InChIKey
DIIIISSCIXVANO-UHFFFAOYSA-N
SMILES
CNNC
MeSH Unique ID
D019813
Source
PubChem CID 1322

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • 1,2-Dimethyl-hydrazine
  • N,N'-Dimethylhydrazine
  • 1,2 Dimethyl hydrazine
  • 1,2 Dimethylhydrazine
  • N,N' Dimethylhydrazine
  • SDMH
  • sym-Dimethylhydrazine
  • sym Dimethylhydrazine

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

98; use 1,2-DIMETHYLHYDRAZINE (NM) 1980-97

MeSH Record

Previous Indexing

  • Dimethylhydrazines (1977-1997)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. 1,2-Dimethylhydrazine. Medical Subject Headings (MeSH). 2026. Unique ID D019813. http://id.nlm.nih.gov/mesh/2026/D019813
  2. 1,2-Dimethylhydrazine. In: Wikipedia. https://en.wikipedia.org/wiki/Symmetrical_dimethylhydrazine
  3. 1,2-Dimethylhydrazine. In: Wikidata. https://www.wikidata.org/wiki/Q161484
  4. 1,2-Dimethylhydrazine. In: PubChem Compound. CID 1322. https://pubchem.ncbi.nlm.nih.gov/compound/1322