Structured Summary
Abstract
A cell adhesion molecule that, in humans, is encoded by a gene on the PSEUDOAUTOSOMAL REGION of SEX CHROMOSOMES. It functions in CELL ADHESION of T-LYMPHOCYTES and ROSETTE FORMATION by ERYTHROCYTES. It is also involved in the migration of LEUKOCYTES through the ENDOTHELIUM BASEMENT MEMBRANE. The 12E7 antigen co-localizes with, but functions independently of PECAM-1.
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Classification
Broader headings
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Synonyms
12 entry terms
- 12E7 Protein
- Antigens, CD99
- CD99 Antigen
- CD99 Molecule
- E2 Antigen
- MIC2 Protein
- T-Cell Surface Glycoprotein E2
- Antigen, 12E7
- Antigen, CD99
- Antigen, E2
- CD99 Antigens
- T Cell Surface Glycoprotein E2
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2018 (2017)
MeSH Record
Previous Indexing
- Antigens, CD (2004-2016)
- Cell Adhesion Molecules (2004-2016)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. 12E7 Antigen. Medical Subject Headings (MeSH). 2026. Unique ID D000071443. http://id.nlm.nih.gov/mesh/2026/D000071443
- 12E7 Antigen. In: Wikipedia. https://en.wikipedia.org/wiki/CD99
- 12E7 Antigen. In: Wikidata. https://www.wikidata.org/wiki/Q21204150