Structured Summary
Abstract
A large family of signal-transducing adaptor proteins present in wide variety of eukaryotes. They are PHOSPHOSERINE and PHOSPHOTHREONINE binding proteins involved in important cellular processes including SIGNAL TRANSDUCTION; CELL CYCLE control; APOPTOSIS; and cellular stress responses. 14-3-3 proteins function by interacting with other signal-transducing proteins and effecting changes in their enzymatic activity and subcellular localization. The name 14-3-3 derives from numerical designations used in the original fractionation patterns of the proteins.
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Synonyms
45 entry terms
- 14-3-3 Protein
- Brain 14-3-3 Protein
- Protein 14-3-3
- 14 3 3 Protein
- 14 3 3 Proteins
- 14-3-3 Protein, Brain
- Brain 14 3 3 Protein
- 14-3-3 Protein, beta Isoform
- 14-3-3 Protein, epsilon Isoform
- 14-3-3 Protein, eta Isoform
- 14-3-3 Protein, gamma Isoform
- 14-3-3 Protein, tau Isoform
- 14-3-3 Protein, zeta Isoform
- 14-3-3 beta Protein
- 14-3-3 epsilon Protein
- 14-3-3 eta Protein
- 14-3-3 gamma Protein
- 14-3-3 tau Protein
- 14-3-3 zeta Protein
- 14-3-3beta Protein
- 14-3-3epsilon Protein
- 14-3-3eta Protein
- 14-3-3gamma Protein
- 14-3-3tau Protein
- 14-3-3zeta Protein
- 14 3 3 Protein, beta Isoform
- 14 3 3 Protein, epsilon Isoform
- 14 3 3 Protein, eta Isoform
- 14 3 3 Protein, gamma Isoform
- 14 3 3 Protein, tau Isoform
- 14 3 3 Protein, zeta Isoform
- 14 3 3 beta Protein
- 14 3 3 epsilon Protein
- 14 3 3 eta Protein
- 14 3 3 gamma Protein
- 14 3 3 tau Protein
- 14 3 3 zeta Protein
- 14 3 3beta Protein
- 14 3 3epsilon Protein
- 14 3 3eta Protein
- 14 3 3gamma Protein
- 14 3 3tau Protein
- 14 3 3zeta Protein
- Protein, 14-3-3tau
- eta Protein, 14-3-3
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2005(1981)
MeSH Record
Previous Indexing
- Nerve Tissue Proteins (1981-1994)
- Proteins (1995-1999)
- Tyrosine 3-Monooxygenase (2000-2004)
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References
- National Library of Medicine. 14-3-3 Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D048948. http://id.nlm.nih.gov/mesh/2026/D048948
- 14-3-3 Proteins. In: Wikipedia. https://en.wikipedia.org/wiki/14-3-3_protein
- 14-3-3 Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q24780194