Chemicals and Drugs

15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid

A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions include mimicking the hydro-osmotic effect of VASOPRESSIN and activation of TYPE C PHOSPHOLIPASES. (From J Pharmacol Exp Ther 1983;224(1): 108-117; Biochem J 1984;222(1):103-110)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions include mimicking the hydro-osmotic effect of VASOPRESSIN and activation of TYPE C PHOSPHOLIPASES. (From J Pharmacol Exp Ther 1983;224(1): 108-117; Biochem J 1984;222(1):103-110)

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

14 entry terms
  • (15S)-Hydroxy-11 alpha, 9 alpha-(epoxymethano)prosta-5Z, 13E-dienoic Acid
  • (15S)hydroxy-9alpha,11alpha-(epoxymethano)prosta-5,13-dienoic acid
  • 11 alpha,9 alpha-Epoxymethano PGH2
  • 9,11-Dideoxy-11 alpha,9 alpha-epoxymethanoprostaglandin F2 alpha
  • 9,11-Dideoxy-11 alpha,9-alpha-epoxymethano-PGF2 alpha
  • 9,11-epoxymethano-PGH2
  • 11 alpha,9 alpha Epoxymethano PGH2
  • 9,11 epoxymethano PGH2
  • U-44619
  • U-46619
  • U44619
  • U46619
  • U 44619
  • U 46619

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1998; use 15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID (NM) 1977-1997; for (15S)HYDROXY-9ALPHA,11ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID and 9,11-EPOXYMETHANO-PGH2 use PROSTAGLANDIN H2 (NM) 1992-2003

MeSH Record

Previous Indexing

  • Prostaglandin Endoperoxides, Synthetic (1978-1997)
  • Thromboxane A2/analogs & derivatives (1983-1997)

MeSH Hierarchy

Tree Numbers

  1. D01w.248w.497w.158w.685w.750w.744.650.500w.500
  2. D01w.339w.431w.374w.744.650.500w.500
  3. D01w.650w.550w.750w.700.650.500w.500
  4. D02w.389w.593w.374w.744.650.500w.500
  5. D10w.251w.355w.255w.550w.025.650.500w.500
  6. D23.469.050w.175w.725w.025.650.500w.500
  7. D23.469.700.630.500

AMA Style

References

  1. National Library of Medicine. 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D019796. http://id.nlm.nih.gov/mesh/2026/D019796
  2. 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q73616080