Chemicals and Drugs

2-Aminoadipic Acid

A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).

MeSH Record

Classification

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • 2 Aminoadipic Acid
  • 2-Aminohexanedioic Acid
  • alpha-Aminoadipic Acid
  • 2 Aminohexanedioic Acid
  • Acid, 2 Aminoadipic
  • Acid, 2-Aminoadipic
  • Acid, 2-Aminohexanedioic
  • Acid, alpha-Aminoadipic
  • Aminoadipic Acid, 2
  • alpha Aminoadipic Acid

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(76); was see under AMINO ACIDS, DICARBOXYLIC 1976-90

MeSH Record

Previous Indexing

  • Adipic Acids (1969-1975)
  • Amino Acids, Dicarboxylic (1974-1975)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. 2-Aminoadipic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D015074. http://id.nlm.nih.gov/mesh/2026/D015074
  2. 2-Aminoadipic Acid. In: Wikipedia. https://en.wikipedia.org/wiki/%CE%91-Aminoadipic_acid
  3. 2-Aminoadipic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q2823204