Structured Summary
Abstract
A chemical reagent that reacts with and modifies chemically the tryptophan portion of protein molecules. Used for 'active site' enzyme studies and other protein studies. Sometimes referred to as Koshland's reagent.
Chemical Identity
Chemical Information
- Molecular Formula
- C7H6BrNO3
- Molecular Weight
- 232.03 g/mol
- CAS Registry No.
- 772-33-8
- IUPAC Name
- 2-(bromomethyl)-4-nitrophenol
- InChIKey
- KFDPCYZHENQOBV-UHFFFAOYSA-N
- SMILES
- C1=CC(=C(C=C1[N+](=O)[O-])CBr)O
- MeSH Unique ID
- D015077
- Source
- PubChem CID 13044
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
9 entry terms
- Koshland Reagent
- Koshland's Reagent I
- Koshlands Reagent
- 2 Hydroxy 5 nitrobenzyl Bromide
- Koshland Reagent I
- Koshlands Reagent I
- Reagent I, Koshland's
- Reagent, Koshland
- Reagent, Koshlands
MeSH Record
Aspects Covered
19 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analogs & derivatives, analysis, chemical synthesis, chemistry, classification, economics, history, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity.
MeSH Record
History Note
91(75); was see under NITROPHENOLS 1975-90
MeSH Record
Previous Indexing
- Benzyl Compounds (1973-1974)
- Nitrophenols (1973-1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. 2-Hydroxy-5-nitrobenzyl Bromide. Medical Subject Headings (MeSH). 2026. Unique ID D015077. http://id.nlm.nih.gov/mesh/2026/D015077
- 2-Hydroxy-5-nitrobenzyl Bromide. In: Wikidata. https://www.wikidata.org/wiki/Q67617749
- 2-Hydroxy-5-nitrobenzyl Bromide. In: PubChem Compound. CID 13044. https://pubchem.ncbi.nlm.nih.gov/compound/13044