Structured Summary
Abstract
An enzyme that catalyzes the first step in the biosynthetic pathway to LEUCINE, forming isopropyl malate from acetyl-CoA and alpha-ketoisovaleric acid. This enzyme was formerly listed as EC 4.1.3.12.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
5 entry terms
- alpha-Isopropylmalate Synthase
- 2 Isopropylmalate Synthase
- Synthase, 2-Isopropylmalate
- Synthase, alpha-Isopropylmalate
- alpha Isopropylmalate Synthase
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
91(75); was see under KETOACID-LYASES 1975-90
MeSH Record
Previous Indexing
- Ketoacid-Lyases (1973-1974)
- Ketoacids (1973-1974)
- Malates (1973-1974)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. 2-Isopropylmalate Synthase. Medical Subject Headings (MeSH). 2026. Unique ID D015079. http://id.nlm.nih.gov/mesh/2026/D015079
- 2-Isopropylmalate Synthase. In: Wikipedia. https://en.wikipedia.org/wiki/2-isopropylmalate_synthase
- 2-Isopropylmalate Synthase. In: Wikidata. https://www.wikidata.org/wiki/Q24744743