Structured Summary
Abstract
An NAD+ dependent enzyme that catalyzes the oxidation 3-methyl-2-oxobutanoate to 2-methylpropanoyl-CoA. It plays a role in the degradation of VALINE; LEUCINE; and ISOLEUCINE.
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Classification
Broader headings
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Synonyms
6 entry terms
- 2-Oxoisovalerate Dehydrogenase
- alpha-Ketoisovalerate Dehydrogenase
- 2 Oxoisovalerate Dehydrogenase
- Dehydrogenase, 2-Oxoisovalerate
- Dehydrogenase, alpha-Ketoisovalerate
- alpha Ketoisovalerate Dehydrogenase
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006(1980); use AMINO ACIDS, BRANCHED-CHAIN 1979, & KETO ACIDS & VALERATES 1973-1979
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AMA Style
References
- National Library of Medicine. 2-Oxoisovalerate Dehydrogenase (Acylating). Medical Subject Headings (MeSH). 2026. Unique ID D050645. http://id.nlm.nih.gov/mesh/2026/D050645
- 2-Oxoisovalerate Dehydrogenase (Acylating). In: Wikipedia. https://en.wikipedia.org/wiki/2-oxoisovalerate_dehydrogenase_(acylating)
- 2-Oxoisovalerate Dehydrogenase (Acylating). In: Wikidata. https://www.wikidata.org/wiki/Q3598023