Chemicals and Drugs

2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine

A selective D1 dopamine receptor agonist used primarily as a research tool.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A selective D1 dopamine receptor agonist used primarily as a research tool.

Chemical Identity

Chemical Information

Molecular Formula
C16H17NO2
Molecular Weight
255.31 g/mol
CAS Registry No.
67287-49-4
IUPAC Name
5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
InChIKey
JUDKOGFHZYMDMF-UHFFFAOYSA-N
SMILES
C1CNCC(C2=CC(=C(C=C21)O)O)C3=CC=CC=C3
MeSH Unique ID
D015647
Source
PubChem CID 1242

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

12 entry terms
  • 1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-
  • R-SK&F 38393
  • SK&F-38393
  • SKF 38393-A
  • SKF-38393
  • SKF38393
  • RSK&F 38393
  • SK&F 38393
  • SK&F38393
  • SKF 38393
  • SKF 38393 A
  • SKF 38393A

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2005(1990)

MeSH Record

Previous Indexing

  • Benzazepines (1966-1989)
  • Dopaminergic Agents (1989)

MeSH Hierarchy

Tree Number

  1. D03w.633.100.079.838w

AMA Style

References

  1. National Library of Medicine. 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine. Medical Subject Headings (MeSH). 2026. Unique ID D015647. http://id.nlm.nih.gov/mesh/2026/D015647
  2. 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine. In: Wikipedia. https://en.wikipedia.org/wiki/SKF-38,393
  3. 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine. In: Wikidata. https://www.wikidata.org/wiki/Q7390598
  4. 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine. In: PubChem Compound. CID 1242. https://pubchem.ncbi.nlm.nih.gov/compound/1242