Anatomy

3T3 Cells

Cell lines whose original growing procedure consisted being transferred (T) every 3 days and plated at 300,000 cells per plate (J Cell Biol 17:299-313, 1963). Lines have been developed using several different strains of mice. Tissues are usually fibroblasts derived from mouse embryos but other types and sources have been developed as well. The 3T3 lines are valuable in vitro host systems for oncogenic virus transformation studies, since 3T3 cells possess a high sensitivity to CONTACT INHIBITION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Cell lines whose original growing procedure consisted being transferred (T) every 3 days and plated at 300,000 cells per plate (J Cell Biol 17:299-313, 1963). Lines have been developed using several different strains of mice. Tissues are usually fibroblasts derived from mouse embryos but other types and sources have been developed as well. The 3T3 lines are valuable in vitro host systems for oncogenic virus transformation studies, since 3T3 cells possess a high sensitivity to CONTACT INHIBITION.

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MeSH Record

Synonyms

3 entry terms
  • 3T3 Cell
  • Cell, 3T3
  • Cells, 3T3

MeSH Record

Aspects Covered

15 allowable subheadings

Indexed with the subheadings chemistry, classification, cytology, drug effects, enzymology, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.

MeSH Record

Indexing Annotation

almost always NIM with no subheadings; check ANIMALS & MICE; do not routinely add FIBROBLASTS or EMBRYO, MAMMALIAN

MeSH Record

History Note

1992

MeSH Record

Previous Indexing

  • Cell Line (1966-1991)

MeSH Hierarchy

Tree Numbers

  1. A11w.251.210w.100w
  2. A11w.329w.228w.100w

AMA Style

References

  1. National Library of Medicine. 3T3 Cells. Medical Subject Headings (MeSH). 2026. Unique ID D016475. http://id.nlm.nih.gov/mesh/2026/D016475
  2. 3T3 Cells. In: Wikipedia. https://en.wikipedia.org/wiki/3T3_cells
  3. 3T3 Cells. In: Wikidata. https://www.wikidata.org/wiki/Q68153243