Chemicals and Drugs

4-Chloro-7-nitrobenzofurazan

A benzofuran derivative used as a protein reagent since the terminal N-NBD-protein conjugate possesses interesting fluorescence and spectral properties. It has also been used as a covalent inhibitor of both beef heart mitochondrial ATPase and bacterial ATPase.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A benzofuran derivative used as a protein reagent since the terminal N-NBD-protein conjugate possesses interesting fluorescence and spectral properties. It has also been used as a covalent inhibitor of both beef heart mitochondrial ATPase and bacterial ATPase.

Chemical Identity

Chemical Information

Molecular Formula
C6H2ClN3O3
Molecular Weight
199.55 g/mol
CAS Registry No.
10199-89-0
IUPAC Name
4-chloro-7-nitro-2,1,3-benzoxadiazole
InChIKey
IGHBXJSNZCFXNK-UHFFFAOYSA-N
SMILES
C1=C(C2=NON=C2C(=C1)Cl)[N+](=O)[O-]
MeSH Unique ID
D009327
Source
PubChem CID 25043

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • 7-Chloro-4-nitrobenzofurazan
  • Chloronitrobenzoxadiazole
  • NBD Chloride
  • NBF-Cl
  • Nitrobenzoxadiazole Chloride
  • 4 Chloro 7 nitrobenzofurazan
  • 7 Chloro 4 nitrobenzofurazan
  • Chloride, NBD
  • Chloride, Nitrobenzoxadiazole
  • NBF Cl

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2001(1976);

MeSH Record

Previous Indexing

  • Nitro Compounds (1974-1975)
  • Oxadiazoles (1972-1975)

MeSH Hierarchy

Tree Number

  1. D03w.383.129w.462.580w.400

AMA Style

References

  1. National Library of Medicine. 4-Chloro-7-nitrobenzofurazan. Medical Subject Headings (MeSH). 2026. Unique ID D009327. http://id.nlm.nih.gov/mesh/2026/D009327
  2. 4-Chloro-7-nitrobenzofurazan. In: Wikidata. https://www.wikidata.org/wiki/Q229939
  3. 4-Chloro-7-nitrobenzofurazan. In: PubChem Compound. CID 25043. https://pubchem.ncbi.nlm.nih.gov/compound/25043