Structured Summary
Abstract
A methylated nucleotide base found in eukaryotic DNA. In ANIMALS, the DNA METHYLATION of CYTOSINE to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In PLANTS, the methylated sequence is CpNpGp, where N can be any base.
Chemical Identity
Chemical Information
- Molecular Formula
- C5H7N3O
- Molecular Weight
- 125.13 g/mol
- CAS Registry No.
- 554-01-8
- IUPAC Name
- 6-amino-5-methyl-1H-pyrimidin-2-one
- InChIKey
- LRSASMSXMSNRBT-UHFFFAOYSA-N
- SMILES
- CC1=C(NC(=O)N=C1)N
- MeSH Unique ID
- D044503
- Source
- PubChem CID 65040
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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MeSH Record
Synonyms
4 entry terms
- 5 Methylcytosine
- 5-Methylcytosine Monohydrochloride
- 5 Methylcytosine Monohydrochloride
- Monohydrochloride, 5-Methylcytosine
MeSH Record
Aspects Covered
27 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2004; use 5-METHYLCYTOSINE (NM) 1980-2003
MeSH Record
Previous Indexing
- Cytosine (1970-2003)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. 5-Methylcytosine. Medical Subject Headings (MeSH). 2026. Unique ID D044503. http://id.nlm.nih.gov/mesh/2026/D044503
- 5-Methylcytosine. In: Wikipedia. https://en.wikipedia.org/wiki/5-Methylcytosine
- 5-Methylcytosine. In: Wikidata. https://www.wikidata.org/wiki/Q238563
- 5-Methylcytosine. In: PubChem Compound. CID 65040. https://pubchem.ncbi.nlm.nih.gov/compound/65040