Chemicals and Drugs

5'-Nucleotidase

A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

23 entry terms
  • 5'-AMP Nucleotidase
  • 5'-Nucleotidase Phosphoribolase
  • AMP Phosphatase
  • Adenylate Phosphatase
  • Antigen, CD73
  • Antigens, CD73
  • CD73 Antigens
  • Cytidylate Phosphatase
  • Ecto-5'-Nucleotidase
  • IMP Nucleotidase
  • IMP Phosphatase
  • IMPase
  • Inosinate Phosphatase
  • Pyrimidine 5'-Nucleotidase
  • Thymidine Phosphatase
  • Uridylate 5'-Nucleotidase
  • 5' AMP Nucleotidase
  • 5' Nucleotidase
  • 5' Nucleotidase Phosphoribolase
  • CD73 Antigen
  • Ecto 5' Nucleotidase
  • Pyrimidine 5' Nucleotidase
  • Uridylate 5' Nucleotidase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

1990; for CD73 ANTIGENS use CD73 ANTIGEN 1992-93

MeSH Record

Previous Indexing

  • Nucleotidases (1966-1989)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. 5'-Nucleotidase. Medical Subject Headings (MeSH). 2026. Unique ID D015720. http://id.nlm.nih.gov/mesh/2026/D015720
  2. 5'-Nucleotidase. In: Wikipedia. https://en.wikipedia.org/wiki/5%27-nucleotidase
  3. 5'-Nucleotidase. In: Wikidata. https://www.wikidata.org/wiki/Q24775951