Structured Summary
Abstract
Tryptamine substituted with two hydroxyl groups in positions 5 and 6. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacologic research.
Chemical Identity
Chemical Information
- Molecular Formula
- C10H12N2O2
- Molecular Weight
- 192.21 g/mol
- CAS Registry No.
- 5090-36-8
- IUPAC Name
- 3-(2-aminoethyl)-1H-indole-5,6-diol
- InChIKey
- SKOKLDQYOKPCPU-UHFFFAOYSA-N
- SMILES
- C1=C2C(=CC(=C1O)O)NC=C2CCN
- MeSH Unique ID
- D015115
- Source
- PubChem CID 21163
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
2 entry terms
- 3-(2-Aminoethyl)indole-5,6-diol
- 5,6 Dihydroxytryptamine
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
78(75); was see under TRYPTAMINES 1975-77
MeSH Record
Previous Indexing
- Tryptamines (1966-1974)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. 5,6-Dihydroxytryptamine. Medical Subject Headings (MeSH). 2026. Unique ID D015115. http://id.nlm.nih.gov/mesh/2026/D015115
- 5,6-Dihydroxytryptamine. In: Wikipedia. https://en.wikipedia.org/wiki/5,6-Dihydroxytryptamine
- 5,6-Dihydroxytryptamine. In: Wikidata. https://www.wikidata.org/wiki/Q27292226
- 5,6-Dihydroxytryptamine. In: PubChem Compound. CID 21163. https://pubchem.ncbi.nlm.nih.gov/compound/21163