Chemicals and Drugs

5,7-Dihydroxytryptamine

Tryptamine substituted with two hydroxyl groups in positions 5 and 7. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacology as a tool.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Tryptamine substituted with two hydroxyl groups in positions 5 and 7. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacology as a tool.

Chemical Identity

Chemical Information

Molecular Formula
C10H12N2O2
Molecular Weight
192.21 g/mol
CAS Registry No.
31363-74-3
IUPAC Name
3-(2-aminoethyl)-1H-indole-5,7-diol
InChIKey
LXWHQTNFZDTKBH-UHFFFAOYSA-N
SMILES
C1=C(C=C(C2=C1C(=CN2)CCN)O)O
MeSH Unique ID
D015116
Source
PubChem CID 35781

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • 3-(2-Aminoethyl)-1H-indole-5,7-diol
  • 5,7 Dihydroxytryptamine
  • 5,7-Dihydroxytryptamine Creatine Sulfate
  • 5,7 Dihydroxytryptamine Creatine Sulfate
  • Creatine Sulfate, 5,7-Dihydroxytryptamine
  • Sulfate, 5,7-Dihydroxytryptamine Creatine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(78); was see under DIHYDROXYTRYPTAMINES 1978-90

MeSH Record

Previous Indexing

  • Tryptamines (1966-1977)

MeSH Hierarchy

Tree Number

  1. D03w.633.100.473.914w.201w.263w

AMA Style

References

  1. National Library of Medicine. 5,7-Dihydroxytryptamine. Medical Subject Headings (MeSH). 2026. Unique ID D015116. http://id.nlm.nih.gov/mesh/2026/D015116
  2. 5,7-Dihydroxytryptamine. In: Wikipedia. https://en.wikipedia.org/wiki/5,7-Dihydroxytryptamine
  3. 5,7-Dihydroxytryptamine. In: Wikidata. https://www.wikidata.org/wiki/Q977151
  4. 5,7-Dihydroxytryptamine. In: PubChem Compound. CID 35781. https://pubchem.ncbi.nlm.nih.gov/compound/35781