Structured Summary
Abstract
An immortalized cell line derived from human ADENOCARCINOMA, ALVEOLAR basal epithelial cells isolated from the lungs of a male patient in 1972. The cell line is positive for KERATIN, can synthesize LECITHIN, and contains high levels of POLYUNSATURATED FATTY ACIDS in its PLASMA MEMBRANE. It is used as a model for PULMONARY ALVEOLI function and virus infections, as a TRANSFECTION host, and for PRECLINICAL DRUG EVALUATION.
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Classification
Broader headings
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Synonyms
7 entry terms
- A549 Cell Line
- A549 Cell
- A549 Cell Lines
- Cell Line, A549
- Cell Lines, A549
- Cell, A549
- Cells, A549
MeSH Record
Aspects Covered
15 allowable subheadings
Indexed with the subheadings chemistry, classification, cytology, drug effects, enzymology, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.
MeSH Record
Indexing Annotation
almost always NIM with no subheadings; check HUMAN; do not routinely add ADENOCARCINOMA, ALVEOLAR
MeSH Record
History Note
2017
MeSH Record
Previous Indexing
- Adenocarcinoma, Bronchiolo-Alveolar (1980-2016)
- Cell Line (1980-2016)
- Cell Line, Tumor (2004-2016)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. A549 Cells. Medical Subject Headings (MeSH). 2026. Unique ID D000072283. http://id.nlm.nih.gov/mesh/2026/D000072283
- A549 Cells. In: Wikipedia. https://en.wikipedia.org/wiki/A549_cell
- A549 Cells. In: Wikidata. https://www.wikidata.org/wiki/Q4649475