Phenomena and Processes

AT-Hook Motifs

DNA-binding motifs, first described in one of the HMGA PROTEINS: HMG-I(Y) PROTEIN. They consist of positively charged sequences of nine amino acids centered on the invariant tripeptide glycine-arginine-proline. They act to fasten the protein to an AT RICH SEQUENCE in the DNA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

DNA-binding motifs, first described in one of the HMGA PROTEINS: HMG-I(Y) PROTEIN. They consist of positively charged sequences of nine amino acids centered on the invariant tripeptide glycine-arginine-proline. They act to fasten the protein to an AT RICH SEQUENCE in the DNA.

MeSH Record

Classification

Broader headings

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See Also

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Synonyms

11 entry terms
  • AT Hook Motif
  • AT Hooks
  • AT Hook
  • AT Hook Motifs
  • AT-Hook Motif
  • Hook, AT
  • Hooks, AT
  • Motif, AT Hook
  • Motif, AT-Hook
  • Motifs, AT Hook
  • Motifs, AT-Hook

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2002

MeSH Record

Previous Indexing

  • DNA-Binding Proteins (1994-2001)

MeSH Hierarchy

Tree Number

  1. G02.111.570.820w.709.275.500.050w

AMA Style

References

  1. National Library of Medicine. AT-Hook Motifs. Medical Subject Headings (MeSH). 2026. Unique ID D024761. http://id.nlm.nih.gov/mesh/2026/D024761
  2. AT-Hook Motifs. In: Wikipedia. https://en.wikipedia.org/wiki/AT-hook
  3. AT-Hook Motifs. In: Wikidata. https://www.wikidata.org/wiki/Q24722372