Structured Summary
Abstract
An androstene derivative that inhibits STEROID 17-ALPHA-HYDROXYLASE and is used as an ANTINEOPLASTIC AGENT in the treatment of metastatic castration-resistant PROSTATE CANCER.
Chemical Identity
Chemical Information
- Molecular Formula
- C26H33NO2
- Molecular Weight
- 391.5 g/mol
- CAS Registry No.
- 154229-18-2
- IUPAC Name
- [(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-pyridin-3-yl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
- InChIKey
- UVIQSJCZCSLXRZ-UBUQANBQSA-N
- SMILES
- CC(=O)O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CC=C4C5=CN=CC=C5)C)C
- MeSH Unique ID
- D000069501
- Source
- PubChem CID 9821849
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
Drug Class
Pharmacological Action
MeSH Record
Synonyms
5 entry terms
- 17-(3-pyridyl)-5,16-androstadien-3beta-acetate
- CB 7630
- CB-7630
- CB7630
- Zytiga
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2016 (1994)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Abiraterone Acetate. Medical Subject Headings (MeSH). 2026. Unique ID D000069501. http://id.nlm.nih.gov/mesh/2026/D000069501
- Abiraterone Acetate. In: Wikipedia. https://en.wikipedia.org/wiki/Abiraterone_acetate
- Abiraterone Acetate. In: Wikidata. https://www.wikidata.org/wiki/Q27888393
- Abiraterone Acetate. In: PubChem Compound. CID 9821849. https://pubchem.ncbi.nlm.nih.gov/compound/9821849