Chemicals and Drugs

Acetoxyacetylaminofluorene

An alkylating agent that forms DNA ADDUCTS at the C-8 position in GUANINE, resulting in single strand breaks. It has demonstrated carcinogenic action.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An alkylating agent that forms DNA ADDUCTS at the C-8 position in GUANINE, resulting in single strand breaks. It has demonstrated carcinogenic action.

Chemical Identity

Chemical Information

Molecular Formula
C17H15NO3
Molecular Weight
281.30 g/mol
CAS Registry No.
6098-44-8
IUPAC Name
[acetyl(9H-fluoren-2-yl)amino] acetate
InChIKey
NFOMHWALMFWNAQ-UHFFFAOYSA-N
SMILES
CC(=O)N(C1=CC2=C(C=C1)C3=CC=CC=C3C2)OC(=O)C
MeSH Unique ID
D000099
Source
PubChem CID 22469

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • Acetoxyacetamidofluorene
  • Acetoxyfluorenylacetamide
  • N-Acetoxy-2-acetylaminofluorene
  • N-Acetoxy-N-acetyl-2-aminofluorene
  • N Acetoxy 2 acetylaminofluorene
  • N Acetoxy N acetyl 2 aminofluorene

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under 2-ACETYLAMINOFLUORENE/analogs & derivatives 1980-90; was see under FLUORENES 1975-79

MeSH Record

Previous Indexing

  • Acetamides (1973-1974)
  • Acetates (1966-1967)
  • Acetic Acids (1968-1972)
  • Amides (1966-1972)
  • Fluorenes (1966-1974)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.064.150w.100w
  2. D02w.241w.081.018w.110.080w.070w
  3. D02w.455w.426w.559w.847w.389.050w.060w
  4. D04w.615w.389.050w.060w

AMA Style

References

  1. National Library of Medicine. Acetoxyacetylaminofluorene. Medical Subject Headings (MeSH). 2026. Unique ID D000099. http://id.nlm.nih.gov/mesh/2026/D000099
  2. Acetoxyacetylaminofluorene. In: Wikipedia. https://en.wikipedia.org/wiki/Acetoxyacetylaminofluorene
  3. Acetoxyacetylaminofluorene. In: Wikidata. https://www.wikidata.org/wiki/Q4673285
  4. Acetoxyacetylaminofluorene. In: PubChem Compound. CID 22469. https://pubchem.ncbi.nlm.nih.gov/compound/22469