Chemicals and Drugs

Acetyl Coenzyme A

Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.

Chemical Identity

Chemical Information

Molecular Formula
C23H38N7O17P3S
Molecular Weight
809.6 g/mol
CAS Registry No.
72-89-9
IUPAC Name
S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] ethanethioate
InChIKey
ZSLZBFCDCINBPY-ZSJPKINUSA-N
SMILES
CC(=O)SCCNC(=O)CCNC(=O)[C@@H](C(C)(C)COP(=O)(O)OP(=O)(O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)O
MeSH Unique ID
D000105
Source
PubChem CID 444493

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

4 entry terms
  • Acetyl CoA
  • Acetyl-CoA
  • CoA, Acetyl
  • Coenzyme A, Acetyl

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

do not confuse with ACYL COENZYME A

MeSH Record

History Note

78(73); was see under COENZYME A 1975-77

MeSH Record

Previous Indexing

  • Coenzyme A (1966-1972)

MeSH Hierarchy

Tree Numbers

  1. D03w.633.100.759.646.138.382w.300w.020w
  2. D08.211w.211w.300w.075w
  3. D13.695w.667.138.382w.300w.020w
  4. D13.695w.827w.068.382w.300w.020w

AMA Style

References

  1. National Library of Medicine. Acetyl Coenzyme A. Medical Subject Headings (MeSH). 2026. Unique ID D000105. http://id.nlm.nih.gov/mesh/2026/D000105
  2. Acetyl Coenzyme A. In: Wikipedia. https://en.wikipedia.org/wiki/Acetyl-CoA
  3. Acetyl Coenzyme A. In: Wikidata. https://www.wikidata.org/wiki/Q715317
  4. Acetyl Coenzyme A. In: PubChem Compound. CID 444493. https://pubchem.ncbi.nlm.nih.gov/compound/444493