Chemicals and Drugs

Acetylglucosaminidase

A beta-N-Acetylhexosaminidase that catalyzes the hydrolysis of terminal, non-reducing 2-acetamido-2-deoxy-beta-glucose residues in chitobiose and higher analogs as well as in glycoproteins. Has been used widely in structural studies on bacterial cell walls and in the study of diseases such as MUCOLIPIDOSIS and various inflammatory disorders of muscle and connective tissue.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A beta-N-Acetylhexosaminidase that catalyzes the hydrolysis of terminal, non-reducing 2-acetamido-2-deoxy-beta-glucose residues in chitobiose and higher analogs as well as in glycoproteins. Has been used widely in structural studies on bacterial cell walls and in the study of diseases such as MUCOLIPIDOSIS and various inflammatory disorders of muscle and connective tissue.

MeSH Record

Classification

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MeSH Record

Synonyms

14 entry terms
  • Chitobiase
  • N,N-Diacetylchitobiase
  • N-Ac-beta-Glucosaminidase
  • N-Acetyl-beta-D-glucosaminidase
  • NAGase
  • beta-D-Acetamido-2-Deoxyglucosidase
  • beta-D-N-acetylglucosaminidase
  • beta-N-Acetylglucosaminidase
  • N Ac beta Glucosaminidase
  • N Acetyl beta D glucosaminidase
  • N,N Diacetylchitobiase
  • beta D Acetamido 2 Deoxyglucosidase
  • beta D N acetylglucosaminidase
  • beta N Acetylglucosaminidase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

do not confuse with BETA-N-ACETYLHEXOSAMINIDASES

MeSH Record

History Note

91(75); was see under GLUCOSAMINIDASE 1975-90

MeSH Record

Previous Indexing

  • Acetamides (1973-1974)
  • Glucosaminidase (1972-1974)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Acetylglucosaminidase. Medical Subject Headings (MeSH). 2026. Unique ID D000118. http://id.nlm.nih.gov/mesh/2026/D000118
  2. Acetylglucosaminidase. In: Wikidata. https://www.wikidata.org/wiki/Q76829435