Chemicals and Drugs

Acid Sensing Ion Channels

A family of proton-gated sodium channels that are primarily expressed in neuronal tissue. They are AMILORIDE-sensitive and are implicated in the signaling of a variety of neurological stimuli, most notably that of pain in response to acidic conditions.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of proton-gated sodium channels that are primarily expressed in neuronal tissue. They are AMILORIDE-sensitive and are implicated in the signaling of a variety of neurological stimuli, most notably that of pain in response to acidic conditions.

MeSH Record

Classification

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MeSH Record

Synonyms

13 entry terms
  • ASIC Channel
  • Acid Sensing Ion Channel
  • Acid-Sensing Ion Channel
  • Acid-Sensing Ion Channels
  • Proton-Gated Sodium Channel
  • Proton-Gated Sodium Channels
  • Channel, Acid-Sensing Ion
  • Channel, Proton-Gated Sodium
  • Ion Channel, Acid-Sensing
  • Proton Gated Sodium Channel
  • Proton Gated Sodium Channels
  • Sodium Channel, Proton-Gated
  • Sodium Channels, Proton-Gated

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2013

MeSH Record

Previous Indexing

  • Sodium Channels (1988-2012)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Acid Sensing Ion Channels. Medical Subject Headings (MeSH). 2026. Unique ID D062565. http://id.nlm.nih.gov/mesh/2026/D062565
  2. Acid Sensing Ion Channels. In: Wikipedia. https://en.wikipedia.org/wiki/Acid-sensing_ion_channel
  3. Acid Sensing Ion Channels. In: Wikidata. https://www.wikidata.org/wiki/Q4222244