Chemicals and Drugs

Actin Depolymerizing Factors

A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel the actin CYTOSKELETON by severing ACTIN FILAMENTS and increasing the rate of monomer dissociation.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel the actin CYTOSKELETON by severing ACTIN FILAMENTS and increasing the rate of monomer dissociation.

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MeSH Record

Synonyms

10 entry terms
  • ADF Proteins (Actin Depolymerizing Factors)
  • Actin Depolymerizing Protein
  • Actin Depolymerizing Proteins
  • Cofilin
  • Cofilin Proteins
  • Cofilins
  • Depolymerizing Factors, Actin
  • Depolymerizing Protein, Actin
  • Depolymerizing Proteins, Actin
  • Protein, Actin Depolymerizing

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1981)

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AMA Style

References

  1. National Library of Medicine. Actin Depolymerizing Factors. Medical Subject Headings (MeSH). 2026. Unique ID D051339. http://id.nlm.nih.gov/mesh/2026/D051339
  2. Actin Depolymerizing Factors. In: Wikipedia. https://en.wikipedia.org/wiki/ADF/Cofilin_family
  3. Actin Depolymerizing Factors. In: Wikidata. https://www.wikidata.org/wiki/Q24786722