Chemicals and Drugs

Adenylosuccinate Lyase

An enzyme that, in the course of purine ribonucleotide biosynthesis, catalyzes the conversion of 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole to 5'-phosphoribosyl-4-carboxamide-5-aminoimidazole and the conversion of adenylosuccinic acid to AMP. EC 4.3.2.2.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that, in the course of purine ribonucleotide biosynthesis, catalyzes the conversion of 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole to 5'-phosphoribosyl-4-carboxamide-5-aminoimidazole and the conversion of adenylosuccinic acid to AMP. EC 4.3.2.2.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

2 entry terms
  • Adenylosuccinase
  • Lyase, Adenylosuccinate

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

91(79); was see under LYASES 1979-90

MeSH Record

Previous Indexing

  • Adenosine Monophosphate (1971-1978)
  • Lyases (1966-1978)
  • Succinates (1966-1978)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Adenylosuccinate Lyase. Medical Subject Headings (MeSH). 2026. Unique ID D000264. http://id.nlm.nih.gov/mesh/2026/D000264
  2. Adenylosuccinate Lyase. In: Wikidata. https://www.wikidata.org/wiki/Q24720351