Diseases

Adie Syndrome

A syndrome characterized by a TONIC PUPIL that occurs in combination with decreased lower extremity reflexes. The affected pupil will respond more briskly to accommodation than to light (light-near dissociation) and is supersensitive to dilute pilocarpine eye drops, which induce pupillary constriction. Pathologic features include degeneration of the ciliary ganglion and postganglionic parasympathetic fibers that innervate the pupillary constrictor muscle. (From Adams et al., Principles of Neurology, 6th ed, p279)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A syndrome characterized by a TONIC PUPIL that occurs in combination with decreased lower extremity reflexes. The affected pupil will respond more briskly to accommodation than to light (light-near dissociation) and is supersensitive to dilute pilocarpine eye drops, which induce pupillary constriction. Pathologic features include degeneration of the ciliary ganglion and postganglionic parasympathetic fibers that innervate the pupillary constrictor muscle. (From Adams et al., Principles of Neurology, 6th ed, p279)

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Synonyms

10 entry terms
  • Adie's Syndrome
  • Holmes-Adie Syndrome
  • Poorly Reacting Pupils
  • Holmes Adie Syndrome
  • Poorly Reacting Pupil
  • Pupil, Poorly Reacting
  • Pupils, Poorly Reacting
  • Syndrome, Adie
  • Syndrome, Adie's
  • Syndrome, Holmes-Adie

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2000 (1963)

MeSH Hierarchy

Tree Numbers

  1. C10w.177.045w
  2. C10w.292w.562.700w.250w
  3. C11w.590.436w.200w
  4. C11w.710.800.180w

AMA Style

References

  1. National Library of Medicine. Adie Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D000270. http://id.nlm.nih.gov/mesh/2026/D000270
  2. Adie Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Adie_syndrome
  3. Adie Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q357067