Chemicals and Drugs

Adrenergic alpha-Antagonists

Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.

MeSH Record

Classification

Broader headings

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See Also

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Synonyms

24 entry terms
  • Adrenergic alpha-Blockers
  • Adrenergic alpha-Receptor Blockaders
  • alpha-Adrenergic Antagonists
  • alpha-Adrenergic Blockers
  • alpha-Adrenergic Blocking Agents
  • alpha-Adrenergic Receptor Blockaders
  • alpha-Blockers, Adrenergic
  • Adrenergic alpha Antagonists
  • Adrenergic alpha Blockers
  • Adrenergic alpha Receptor Blockaders
  • Agents, alpha-Adrenergic Blocking
  • Antagonists, alpha-Adrenergic
  • Blockaders, Adrenergic alpha-Receptor
  • Blockaders, alpha-Adrenergic Receptor
  • Blockers, alpha-Adrenergic
  • Blocking Agents, alpha-Adrenergic
  • Receptor Blockaders, alpha-Adrenergic
  • alpha Adrenergic Antagonists
  • alpha Adrenergic Blockers
  • alpha Adrenergic Blocking Agents
  • alpha Adrenergic Receptor Blockaders
  • alpha Blockers, Adrenergic
  • alpha-Antagonists, Adrenergic
  • alpha-Receptor Blockaders, Adrenergic

MeSH Record

Aspects Covered

22 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

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Indexing Annotation

general or unspecified; prefer specifics; do not confuse with ADRENERGIC ALPHA-AGONISTS

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History Note

95; was ADRENERGIC ALPHA RECEPTOR BLOCKADERS 1969-94 (Prov 1969-72)

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Previous Indexing

  • Sympatholytics (1966-1968)

MeSH Hierarchy

Tree Numbers

  1. D27.505.519w.625.050.200w.100w
  2. D27.505.696.577.050.200w.100w

MeSH Record

NLM Classification

QV 132

AMA Style

References

  1. National Library of Medicine. Adrenergic alpha-Antagonists. Medical Subject Headings (MeSH). 2026. Unique ID D000317. http://id.nlm.nih.gov/mesh/2026/D000317
  2. Adrenergic alpha-Antagonists. In: Wikipedia. https://en.wikipedia.org/wiki/Alpha_blocker
  3. Adrenergic alpha-Antagonists. In: Wikidata. https://www.wikidata.org/wiki/Q1927838