Structured Summary
Abstract
A secreted protein of approximately 131 amino acids that is related to AGOUTI SIGNALING PROTEIN and is also an antagonist of MELANOCORTIN RECEPTOR activity. It is expressed primarily in the HYPOTHALAMUS and the ADRENAL GLAND. As a paracrine signaling molecule, AGRP is known to regulate food intake and body weight. Elevated AGRP has been associated with OBESITY.
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Classification
Broader headings
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Synonyms
3 entry terms
- AGRP Protein
- AGRT Protein
- Agouti Related Protein
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2008 (1997)
MeSH Record
Previous Indexing
- Intercellular Signaling Peptides and Proteins (1998-2007)
- Receptors, Melanocortin (1997-2007)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Agouti-Related Protein. Medical Subject Headings (MeSH). 2026. Unique ID D054369. http://id.nlm.nih.gov/mesh/2026/D054369
- Agouti-Related Protein. In: Wikipedia. https://en.wikipedia.org/wiki/Agouti-related_peptide
- Agouti-Related Protein. In: Wikidata. https://www.wikidata.org/wiki/Q2514134