Structured Summary
Abstract
A 3:1 mixture of alfaxalone with alfadolone acetate that previously had been used as a general anesthetic. It is no longer actively marketed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1445)
Chemical Identity
Chemical Information
- Molecular Formula
- C44H66O8
- Molecular Weight
- 723.0 g/mol
- CAS Registry No.
- 8067-82-1
- IUPAC Name
- (3R,5S,8S,9S,10S,13S,14S,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-11-one;[2-[(3R,5S,8S,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-11-oxo-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
- InChIKey
- YYPNLXNMXQFMHG-GSEHKNNPSA-N
- SMILES
- CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@H](C4)O)C)C.CC(=O)OCC(=O)[C@H]1CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@H](C4)O)C)C
- MeSH Unique ID
- D000530
- Source
- PubChem CID 24732
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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MeSH Record
Synonyms
11 entry terms
- Alfadolone Mixture, Alfaxalone
- Alfatesine
- Alfathesin
- Alphadione
- Alphathesin
- Althesin
- CT-1341
- Glaxovet
- Saffan
- CT 1341
- CT1341
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2001(1975)
MeSH Record
Previous Indexing
- Drug Combinations (1974)
- Hydroxysteroids (1974)
- Pregnanediones (1974)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Alfaxalone Alfadolone Mixture. Medical Subject Headings (MeSH). 2026. Unique ID D000530. http://id.nlm.nih.gov/mesh/2026/D000530
- Alfaxalone Alfadolone Mixture. In: Wikipedia. https://en.wikipedia.org/wiki/Alfaxolone/alfadolone
- Alfaxalone Alfadolone Mixture. In: Wikidata. https://www.wikidata.org/wiki/Q4721889
- Alfaxalone Alfadolone Mixture. In: PubChem Compound. CID 24732. https://pubchem.ncbi.nlm.nih.gov/compound/24732