Chemicals and Drugs

Algestone

A synthetic progestational dihydroxy derivative of PROGESTERONE. Its acetonide possesses anti-inflammatory properties.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A synthetic progestational dihydroxy derivative of PROGESTERONE. Its acetonide possesses anti-inflammatory properties.

Chemical Identity

Chemical Information

Molecular Formula
C21H30O4
Molecular Weight
346.5 g/mol
CAS Registry No.
595-77-7
IUPAC Name
(8R,9S,10R,13S,14S,16R,17S)-17-acetyl-16,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
InChIKey
CXDWHYOBSJTRJU-SRWWVFQWSA-N
SMILES
CC(=O)[C@]1([C@@H](C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O)O
MeSH Unique ID
D000523
Source
PubChem CID 11687

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

4 entry terms
  • 16 alpha,17-Dihydroxypregn-4-ene-3,20-dione
  • Alphasone
  • Dihydroxyprogesterone
  • Pregn-4-ene-3,20-dione, 16,17-dihydroxy-, (16alpha)-

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was ALPHASONE see under ALGESTONE ACETOPHENIDE/analogs & derivatives 1975-90; was ALPHASONE see under ALGESTONE ACETOPHENIDE 1974; DIHYDROXYPROGESTERONE was see ALGESTONE ACETOPHENIDE 1975-76, was see under ALGESTONE ACETOPHENIDE 1974, was heading 1964-73 (Prov)

MeSH Hierarchy

Tree Number

  1. D04w.210.500w.745.745w.654w.829w.025w

AMA Style

References

  1. National Library of Medicine. Algestone. Medical Subject Headings (MeSH). 2026. Unique ID D000523. http://id.nlm.nih.gov/mesh/2026/D000523
  2. Algestone. In: Wikipedia. https://en.wikipedia.org/wiki/Algestone
  3. Algestone. In: Wikidata. https://www.wikidata.org/wiki/Q4724191
  4. Algestone. In: PubChem Compound. CID 11687. https://pubchem.ncbi.nlm.nih.gov/compound/11687