Chemicals and Drugs

Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 3

A dioxygenase and alkylation repair homolog that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. It has a strong preference for SINGLE-STRANDED DNA and may also act on RNA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A dioxygenase and alkylation repair homolog that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. It has a strong preference for SINGLE-STRANDED DNA and may also act on RNA.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

5 entry terms
  • AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase
  • Alkylated DNA Repair Protein AlkB Homolog 3
  • Prostate Cancer Antigen 1
  • AlkB Homolog 3, Alpha Ketoglutarate Dependent Dioxygenase
  • Alpha Ketoglutarate Dependent Dioxygenase AlkB Homolog 3

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017

MeSH Record

Previous Indexing

  • DNA Repair Enzymes (2006-2016)
  • Dioxygenases (2006-2016)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 3. Medical Subject Headings (MeSH). 2026. Unique ID D000071500. http://id.nlm.nih.gov/mesh/2026/D000071500
  2. Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 3. In: Wikidata. https://www.wikidata.org/wiki/Q21131655