Chemicals and Drugs

Alprazolam

A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)

Chemical Identity

Chemical Information

Molecular Formula
C17H13ClN4
Molecular Weight
308.8 g/mol
CAS Registry No.
28981-97-7
IUPAC Name
8-chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
InChIKey
VREFGVBLTWBCJP-UHFFFAOYSA-N
SMILES
CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4
MeSH Unique ID
D000525
Source
PubChem CID 2118

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

19 entry terms
  • Alprazolan
  • Alprox
  • Apo-Alpraz
  • Cassadan
  • D-65MT
  • Esparon
  • Kalma
  • Novo-Alprazol
  • Nu-Alpraz
  • Ralozam
  • Tafil
  • Trankimazin
  • U-31,889
  • Xanax
  • Apo Alpraz
  • D65MT
  • Novo Alprazol
  • Nu Alpraz
  • U31,889

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

87

MeSH Record

Previous Indexing

  • Azepines (1966-1967)
  • Benzazepines (1968-1973)
  • Benzodiazepines (1975-1986)

MeSH Hierarchy

Tree Number

  1. D03w.633.100.079.080w.030w

AMA Style

References

  1. National Library of Medicine. Alprazolam. Medical Subject Headings (MeSH). 2026. Unique ID D000525. http://id.nlm.nih.gov/mesh/2026/D000525
  2. Alprazolam. In: Wikipedia. https://en.wikipedia.org/wiki/Alprazolam
  3. Alprazolam. In: Wikidata. https://www.wikidata.org/wiki/Q319877
  4. Alprazolam. In: PubChem Compound. CID 2118. https://pubchem.ncbi.nlm.nih.gov/compound/2118