Structured Summary
Abstract
4-Aminopyridine derivative that acts as a POTASSIUM CHANNEL blocker to increase release of ACETYLCHOLINE from nerve terminals. It is used in the treatment of CONGENITAL MYASTHENIC SYNDROMES.
Chemical Identity
Chemical Information
- Molecular Formula
- C5H7N3
- Molecular Weight
- 109.13 g/mol
- CAS Registry No.
- 54-96-6
- IUPAC Name
- pyridine-3,4-diamine
- InChIKey
- OYTKINVCDFNREN-UHFFFAOYSA-N
- SMILES
- C1=CN=CC(=C1N)N
- MeSH Unique ID
- D000077770
- Source
- PubChem CID 5918
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
Drug Class
Pharmacological Action
MeSH Record
Synonyms
5 entry terms
- 3,4-Diaminopyridine
- 3,4 Diaminopyridine
- Amifampridine Phosphate
- Firdapse
- Ruzurgi
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2019 (1978)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Amifampridine. Medical Subject Headings (MeSH). 2026. Unique ID D000077770. http://id.nlm.nih.gov/mesh/2026/D000077770
- Amifampridine. In: Wikipedia. https://en.wikipedia.org/wiki/Amifampridine
- Amifampridine. In: Wikidata. https://www.wikidata.org/wiki/Q411707
- Amifampridine. In: PubChem Compound. CID 5918. https://pubchem.ncbi.nlm.nih.gov/compound/5918