Chemicals and Drugs

Amitrole

A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.

Chemical Identity

Chemical Information

Molecular Formula
C2H4N4
Molecular Weight
84.08 g/mol
CAS Registry No.
61-82-5
IUPAC Name
1H-1,2,4-triazol-5-amine
InChIKey
KLSJWNVTNUYHDU-UHFFFAOYSA-N
SMILES
C1=NNC(=N1)N
MeSH Unique ID
D000640
Source
PubChem CID 1639

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

2 entry terms
  • 3-Amino-1,2,4-triazole
  • Aminotriazole

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(72); was see under TRIAZOLES 1972-90

MeSH Record

Previous Indexing

  • Herbicides (1966-1971)
  • Triazoles (1966-1971)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Amitrole. Medical Subject Headings (MeSH). 2026. Unique ID D000640. http://id.nlm.nih.gov/mesh/2026/D000640
  2. Amitrole. In: Wikipedia. https://en.wikipedia.org/wiki/3-Amino-1,2,4-triazole
  3. Amitrole. In: Wikidata. https://www.wikidata.org/wiki/Q423314
  4. Amitrole. In: PubChem Compound. CID 1639. https://pubchem.ncbi.nlm.nih.gov/compound/1639