Chemicals and Drugs

Amyloid

A fibrous protein complex that consists of proteins folded into a specific cross beta-pleated sheet structure. This fibrillar structure has been found as an alternative folding pattern for a variety of functional proteins. Deposits of amyloid in the form of AMYLOID PLAQUES are associated with a variety of degenerative diseases. The amyloid structure has also been found in a number of functional proteins that are unrelated to disease.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A fibrous protein complex that consists of proteins folded into a specific cross beta-pleated sheet structure. This fibrillar structure has been found as an alternative folding pattern for a variety of functional proteins. Deposits of amyloid in the form of AMYLOID PLAQUES are associated with a variety of degenerative diseases. The amyloid structure has also been found in a number of functional proteins that are unrelated to disease.

MeSH Record

Classification

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See Also

MeSH Record

Synonyms

6 entry terms
  • Amyloid Substance
  • Substance, Amyloid
  • Amyloid Fibril
  • Amyloid Fibrils
  • Fibril, Amyloid
  • Fibrils, Amyloid

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

PLAQUE, AMYLOID is also available

MeSH Record

History Note

68; was AMYLOID SUBSTANCE 1963-67 (Cat C heading only 1966-67, Cat A heading only 1963-64)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Amyloid. Medical Subject Headings (MeSH). 2026. Unique ID D000682. http://id.nlm.nih.gov/mesh/2026/D000682
  2. Amyloid. In: Wikipedia. https://en.wikipedia.org/wiki/Amyloid
  3. Amyloid. In: Wikidata. https://www.wikidata.org/wiki/Q6740853