Structured Summary
Abstract
An enzyme fraction from the venom of the Malayan pit viper, Agkistrodon rhodostoma. It catalyzes the hydrolysis of a number of amino acid esters and a limited proteolysis of fibrinogen. It is used clinically to produce controlled defibrination in patients requiring anticoagulant therapy. EC 3.4.21.-.
MeSH Record
Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
8 entry terms
- Agkistrodon Serine Proteinase
- Agkistrodon rhodostoma Venom Protease
- Arvin
- Arvin IRC-50
- Arwin
- Venacil
- Arvin IRC 50
- Arvin IRC50
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
78; was ARVIN see under ENDOPEPTIDASES 1975-77; ARVIN was see ANCROD 1978-95
MeSH Record
Previous Indexing
- Peptide Hydrolases (1972-1974)
- Peptide Peptidohydrolases (1966-1974)
- Venoms (1972-1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Ancrod. Medical Subject Headings (MeSH). 2026. Unique ID D000721. http://id.nlm.nih.gov/mesh/2026/D000721
- Ancrod. In: Wikipedia. https://en.wikipedia.org/wiki/Ancrod
- Ancrod. In: Wikidata. https://www.wikidata.org/wiki/Q2846011