Structured Summary
Abstract
An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.
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Synonyms
12 entry terms
- ANG-(1-8)Octapeptide
- Angiotensin-(1-8) Octapeptide
- 5-L-Isoleucine Angiotensin II
- Angiotensin II, Ile(5)-
- Angiotensin II, Isoleucine(5)-
- Angiotensin II, Val(5)-
- Angiotensin II, Valine(5)-
- Isoleucine(5)-Angiotensin
- Isoleucyl(5)-Angiotensin II
- Valyl(5)-Angiotensin II
- 5 L Isoleucine Angiotensin II
- Angiotensin II, 5-L-Isoleucine
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Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
1974(1963); for ANGIOTENSIN II, ILE(5)- use ANGIOTENSIN II (NM) 1974-1999
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References
- National Library of Medicine. Angiotensin II. Medical Subject Headings (MeSH). 2026. Unique ID D000804. http://id.nlm.nih.gov/mesh/2026/D000804
- Angiotensin II. In: Wikipedia. https://en.wikipedia.org/wiki/Angiotensin_II_(medication)
- Angiotensin II. In: Wikidata. https://www.wikidata.org/wiki/Q412999