Chemicals and Drugs

Anoctamin-1

An anoctamin chloride channel expressed at high levels in the liver, skeletal muscle, and gastrointestinal muscles that functions in transepithelial anion transport and smooth muscle contraction. It is essential for the function of the INTERSTITIAL CELLS OF CAJAL and plays a major role in chloride conduction by airway epithelial cells and in tracheal cartilage development.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An anoctamin chloride channel expressed at high levels in the liver, skeletal muscle, and gastrointestinal muscles that functions in transepithelial anion transport and smooth muscle contraction. It is essential for the function of the INTERSTITIAL CELLS OF CAJAL and plays a major role in chloride conduction by airway epithelial cells and in tracheal cartilage development.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • TMEM16A Protein
  • Transmembrane Protein 16A
  • Anoctamin 1

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2018

MeSH Record

Previous Indexing

  • Chloride Channels (2003-2017)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.530w.400w.175w.032.500
  2. D12.776w.543w.550w.450w.175w.032.500
  3. D12.776w.543w.585w.400w.175w.032.500

AMA Style

References

  1. National Library of Medicine. Anoctamin-1. Medical Subject Headings (MeSH). 2026. Unique ID D000075369. http://id.nlm.nih.gov/mesh/2026/D000075369
  2. Anoctamin-1. In: Wikidata. https://www.wikidata.org/wiki/Q41796818