Chemicals and Drugs

Anthramycin

A broad-spectrum spectrum antineoplastic antibiotic isolated from Streptomyces refuineus var. thermotolerans. It has low toxicity, some activity against Trichomonas and Endamoeba, and inhibits RNA and DNA synthesis. It binds irreversibly to DNA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A broad-spectrum spectrum antineoplastic antibiotic isolated from Streptomyces refuineus var. thermotolerans. It has low toxicity, some activity against Trichomonas and Endamoeba, and inhibits RNA and DNA synthesis. It binds irreversibly to DNA.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

2 entry terms
  • Antramycin
  • Anthramycin, (11a alpha)-Isomer

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under BENZODIAZEPINONES 1975-90

MeSH Record

Previous Indexing

  • Acrylamides (1973-1974)
  • Benzodiazepinones (1974)
  • Pyrroles (1972-1974)

MeSH Hierarchy

Tree Numbers

  1. D03w.633.100.079.080w.070.050w
  2. D03w.633.300.060w

AMA Style

References

  1. National Library of Medicine. Anthramycin. Medical Subject Headings (MeSH). 2026. Unique ID D000876. http://id.nlm.nih.gov/mesh/2026/D000876
  2. Anthramycin. In: Wikipedia. https://en.wikipedia.org/wiki/Anthramycin
  3. Anthramycin. In: Wikidata. https://www.wikidata.org/wiki/Q4773852