Diseases

Anti-Glomerular Basement Membrane Disease

An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.

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MeSH Record

Synonyms

9 entry terms
  • Anti-GBM Disease
  • Goodpasture Syndrome
  • Goodpasture's Syndrome
  • Lung Purpura with Nephritis
  • Anti GBM Disease
  • Anti Glomerular Basement Membrane Disease
  • Goodpastures Syndrome
  • Syndrome, Goodpasture
  • Syndrome, Goodpasture's

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

1998

MeSH Hierarchy

Tree Numbers

  1. C08w.381.483w.156w
  2. C12.050.351.968w.419w.570w.363w.304w
  3. C12.200.777w.419w.570w.363w.304w
  4. C12.950w.419w.570w.363w.304w
  5. C20w.111w.190w

AMA Style

References

  1. National Library of Medicine. Anti-Glomerular Basement Membrane Disease. Medical Subject Headings (MeSH). 2026. Unique ID D019867. http://id.nlm.nih.gov/mesh/2026/D019867
  2. Anti-Glomerular Basement Membrane Disease. In: Wikipedia. https://en.wikipedia.org/wiki/Goodpasture_syndrome
  3. Anti-Glomerular Basement Membrane Disease. In: Wikidata. https://www.wikidata.org/wiki/Q1345792