Phenomena and Processes

Antigenic Modulation

Loss of detectable antigen from the surface of a cell after incubation with antibodies. This is one method in which some tumors escape detection by the immune system. Antigenic modulation of target antigens also reduces the therapeutic effectiveness of treatment by monoclonal antibodies.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Loss of detectable antigen from the surface of a cell after incubation with antibodies. This is one method in which some tumors escape detection by the immune system. Antigenic modulation of target antigens also reduces the therapeutic effectiveness of treatment by monoclonal antibodies.

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Classification

Broader headings

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See Also

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Synonyms

3 entry terms
  • Antigenic Modulations
  • Modulation, Antigenic
  • Modulations, Antigenic

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Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

92

MeSH Record

Previous Indexing

  • Antigen-Antibody Reactions (1968-1989)
  • Antigens, Surface/analysis (1979-1991)
  • Antigens, Surface/immunology (1979-1988)

MeSH Hierarchy

Tree Number

  1. G12.122.140

AMA Style

References

  1. National Library of Medicine. Antigenic Modulation. Medical Subject Headings (MeSH). 2026. Unique ID D016525. http://id.nlm.nih.gov/mesh/2026/D016525
  2. Antigenic Modulation. In: Wikidata. https://www.wikidata.org/wiki/Q71159046