Structured Summary
Abstract
Autoantibodies directed against cytoplasmic constituents of POLYMORPHONUCLEAR LEUKOCYTES and/or MONOCYTES. They are used as specific markers for GRANULOMATOSIS WITH POLYANGIITIS and other diseases, though their pathophysiological role is not clear. ANCA are routinely detected by indirect immunofluorescence with three different patterns: c-ANCA (cytoplasmic), p-ANCA (perinuclear), and atypical ANCA.
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Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
25 entry terms
- ANCA
- Anti-Neutrophil Cytoplasmic Antibodies
- Anti-Neutrophil Cytoplasmic Antibody
- Anti-Neutrophil Cytoplasmic Autoantibodies
- Anti-Neutrophil Cytoplasmic Autoantibody
- Antibodies, Antineutrophil Cytoplasmic
- Antineutrophil Cytoplasmic Antibody
- Neutrophil Cytoplasmic Autoantibodies
- Neutrophil Cytoplasmic Autoantibody
- Anti Neutrophil Cytoplasmic Antibodies
- Anti Neutrophil Cytoplasmic Antibody
- Anti Neutrophil Cytoplasmic Autoantibodies
- Anti Neutrophil Cytoplasmic Autoantibody
- Antibody, Anti-Neutrophil Cytoplasmic
- Antibody, Antineutrophil Cytoplasmic
- Autoantibody, Anti-Neutrophil Cytoplasmic
- Autoantibody, Neutrophil Cytoplasmic
- Cytoplasmic Antibody, Anti-Neutrophil
- Cytoplasmic Antibody, Antineutrophil
- Cytoplasmic Autoantibody, Anti-Neutrophil
- Cytoplasmic Autoantibody, Neutrophil
- c-ANCA
- p-ANCA
- c ANCA
- p ANCA
MeSH Record
Aspects Covered
23 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
do not coordinate with ANTIBODY FORMATION for /biosyn;
MeSH Record
History Note
97; was C-ANCA (NM) 1991-96
MeSH Record
Previous Indexing
- Autoantibodies (1991-1996)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Antineutrophil Cytoplasmic Antibodies. Medical Subject Headings (MeSH). 2026. Unique ID D019268. http://id.nlm.nih.gov/mesh/2026/D019268
- Antineutrophil Cytoplasmic Antibodies. In: Wikipedia. https://en.wikipedia.org/wiki/Anti-neutrophil_cytoplasmic_antibody
- Antineutrophil Cytoplasmic Antibodies. In: Wikidata. https://www.wikidata.org/wiki/Q574727