Chemicals and Drugs

Antithrombins

Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

10 entry terms
  • Antithrombin
  • Direct Antithrombin
  • Direct Antithrombins
  • Direct Thrombin Inhibitor
  • Direct Thrombin Inhibitors
  • Antithrombin, Direct
  • Antithrombins, Direct
  • Inhibitor, Direct Thrombin
  • Thrombin Inhibitor, Direct
  • Thrombin Inhibitors, Direct

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

ANTITHROMBIN PROTEINS is also available

MeSH Record

History Note

2011(1964)

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

QV 193

AMA Style

References

  1. National Library of Medicine. Antithrombins. Medical Subject Headings (MeSH). 2026. Unique ID D000991. http://id.nlm.nih.gov/mesh/2026/D000991
  2. Antithrombins. In: Wikidata. https://www.wikidata.org/wiki/Q50316187