Chemicals and Drugs

Apolipoprotein C-I

A 6.6-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS; INTERMEDIATE-DENSITY LIPOPROTEINS; and HIGH-DENSITY LIPOPROTEINS. Apo C-I displaces APO E from lipoproteins, modulate their binding to receptors (RECEPTORS, LDL), and thereby decrease their clearance from plasma. Elevated Apo C-I levels are associated with HYPERLIPOPROTEINEMIA and ATHEROSCLEROSIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 6.6-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS; INTERMEDIATE-DENSITY LIPOPROTEINS; and HIGH-DENSITY LIPOPROTEINS. Apo C-I displaces APO E from lipoproteins, modulate their binding to receptors (RECEPTORS, LDL), and thereby decrease their clearance from plasma. Elevated Apo C-I levels are associated with HYPERLIPOPROTEINEMIA and ATHEROSCLEROSIS.

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Classification

Broader headings

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MeSH Record

Synonyms

10 entry terms
  • Apo C-I
  • Apolipoprotein C1
  • Apo C I
  • Apolipoprotein C I
  • Apo C-I Precursor
  • Apolipoprotein C-I Precursor
  • Pre Apo C-I
  • Apo C I Precursor
  • Apolipoprotein C I Precursor
  • Pre Apo C I

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007; use APOLIPOPROTEIN C-I (NM) 1979-2006

MeSH Record

Previous Indexing

  • Apolipoproteins C (1977-2006)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Apolipoprotein C-I. Medical Subject Headings (MeSH). 2026. Unique ID D053302. http://id.nlm.nih.gov/mesh/2026/D053302
  2. Apolipoprotein C-I. In: Wikidata. https://www.wikidata.org/wiki/Q24773331