Chemicals and Drugs

Arginine Vasopressin

The predominant form of mammalian antidiuretic hormone. It is a nonapeptide containing an ARGININE at residue 8 and two disulfide-linked cysteines at residues of 1 and 6. Arg-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The predominant form of mammalian antidiuretic hormone. It is a nonapeptide containing an ARGININE at residue 8 and two disulfide-linked cysteines at residues of 1 and 6. Arg-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.

Chemical Identity

Chemical Information

Molecular Formula
C46H65N15O12S2
Molecular Weight
1084.2 g/mol
CAS Registry No.
113-79-1
IUPAC Name
(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
InChIKey
KBZOIRJILGZLEJ-LGYYRGKSSA-N
SMILES
C1C[C@H](N(C1)C(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N
MeSH Unique ID
D001127
Source
PubChem CID 644077

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • Arg-Vasopressin
  • Argipressin
  • Vasopressin, Arginine
  • Arg Vasopressin
  • Argipressin Tannate

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2007 (1979)

MeSH Record

Previous Indexing

  • Arginine (1966-1974)
  • Vasopressins (1966-1974)

MeSH Hierarchy

Tree Numbers

  1. D06.472w.699w.631.692.781.100w
  2. D12.644w.400w.900.100w
  3. D12.644w.456w.925.100w
  4. D12.644w.548w.691.692.781.100w
  5. D12.776w.631w.650w.937.100w

AMA Style

References

  1. National Library of Medicine. Arginine Vasopressin. Medical Subject Headings (MeSH). 2026. Unique ID D001127. http://id.nlm.nih.gov/mesh/2026/D001127
  2. Arginine Vasopressin. In: Wikipedia. https://en.wikipedia.org/wiki/Vasopressin_(medication)
  3. Arginine Vasopressin. In: Wikidata. https://www.wikidata.org/wiki/Q183011
  4. Arginine Vasopressin. In: PubChem Compound. CID 644077. https://pubchem.ncbi.nlm.nih.gov/compound/644077