Chemicals and Drugs

Argininosuccinate Lyase

An enzyme of the urea cycle which splits argininosuccinate to fumarate plus arginine. Its absence leads to the metabolic disease ARGININOSUCCINIC ACIDURIA in man. EC 4.3.2.1.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme of the urea cycle which splits argininosuccinate to fumarate plus arginine. Its absence leads to the metabolic disease ARGININOSUCCINIC ACIDURIA in man. EC 4.3.2.1.

MeSH Record

Classification

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MeSH Record

See Also

MeSH Record

Synonyms

2 entry terms
  • Argininosuccinase
  • Lyase, Argininosuccinate

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

1991(1975); use LYASES 1975-1990

MeSH Record

Previous Indexing

  • Arginine (1973-1974)
  • Lyases (1973-1974)
  • Succinates (1973-1974)

MeSH Hierarchy

Tree Number

  1. D08.811w.520w.232.300.400

AMA Style

References

  1. National Library of Medicine. Argininosuccinate Lyase. Medical Subject Headings (MeSH). 2026. Unique ID D001123. http://id.nlm.nih.gov/mesh/2026/D001123
  2. Argininosuccinate Lyase. In: Wikidata. https://www.wikidata.org/wiki/Q24772456