Anatomy

Artificial Human Chromosomes

DNA constructs that are composed of, at least, all elements, such as a REPLICATION ORIGIN; TELOMERE; and CENTROMERE, required for successful replication, propagation to and maintainance in progeny human cells. In addition, they are constructed to carry other sequences for analysis or gene transfer.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

DNA constructs that are composed of, at least, all elements, such as a REPLICATION ORIGIN; TELOMERE; and CENTROMERE, required for successful replication, propagation to and maintainance in progeny human cells. In addition, they are constructed to carry other sequences for analysis or gene transfer.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

9 entry terms
  • Artificial Chromosomes, Human
  • Chromosomes, Artificial, Human
  • Chromosomes, Human Artificial
  • HAC (Chromosome)
  • HACs (Chromosomes)
  • Human Artificial Chromosomes
  • Artificial Chromosome, Human
  • Chromosome, Human Artificial
  • Human Artificial Chromosome

MeSH Record

Aspects Covered

13 allowable subheadings

Indexed with the subheadings chemistry, classification, drug effects, enzymology, genetics, immunology, metabolism, microbiology, parasitology, physiology, radiation effects, ultrastructure, virology.

MeSH Record

Indexing Annotation

coord with specific human chromosome /genet only if particularly discussed

MeSH Record

History Note

2002(2001)

MeSH Record

Previous Indexing

  • Chromosomes (1992-2000)

MeSH Hierarchy

Tree Numbers

  1. A11w.284w.187w.178.190.117
  2. A11w.284w.187w.520.190.117
  3. A11w.284w.187w.520.300.117
  4. G05.360w.162w.178.190.117
  5. G05.360w.162w.520.190.117
  6. G05.360w.162w.520.300.117
  7. G05.360w.337w.249.190.117

AMA Style

References

  1. National Library of Medicine. Artificial Human Chromosomes. Medical Subject Headings (MeSH). 2026. Unique ID D022222. http://id.nlm.nih.gov/mesh/2026/D022222
  2. Artificial Human Chromosomes. In: Wikidata. https://www.wikidata.org/wiki/Q70076858