Chemicals and Drugs

Atracurium

A non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents.

Chemical Identity

Chemical Information

Molecular Formula
C53H72N2O12+2
Molecular Weight
929.1 g/mol
CAS Registry No.
64228-79-1
IUPAC Name
5-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate
InChIKey
YXSLJKQTIDHPOT-UHFFFAOYSA-N
SMILES
C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C=C6)OC)OC)OC)OC)C
MeSH Unique ID
D001279
Source
PubChem CID 47319

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • 33 A 74
  • Atracurium Besilate
  • Atracurium Besylate
  • Atracurium Dibesylate
  • BW-33A
  • Relatrac
  • Tracrium
  • A 74, 33
  • BW 33A
  • BW33A
  • Besilate, Atracurium

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

87

MeSH Record

Previous Indexing

  • Isoquinolines (1966-1986)

MeSH Hierarchy

Tree Number

  1. D03w.633.100.531.085.061

MeSH Record

NLM Classification

QV 140

AMA Style

References

  1. National Library of Medicine. Atracurium. Medical Subject Headings (MeSH). 2026. Unique ID D001279. http://id.nlm.nih.gov/mesh/2026/D001279
  2. Atracurium. In: Wikidata. https://www.wikidata.org/wiki/Q27098039
  3. Atracurium. In: PubChem Compound. CID 47319. https://pubchem.ncbi.nlm.nih.gov/compound/47319