Diseases

Autoimmune Experimental Myasthenia Gravis

Any autoimmune animal disease model used in the study of MYASTHENIA GRAVIS. Injection with purified neuromuscular junction acetylcholine receptor (AChR) (see RECEPTORS, CHOLINERGIC) components results in a myasthenic syndrome that has acute and chronic phases. The motor endplate pathology, loss of acetylcholine receptors, presence of circulating anti-AChR antibodies, and electrophysiologic changes make this condition virtually identical to human myasthenia gravis. Passive transfer of AChR antibodies or lymphocytes from afflicted animals to normals induces passive transfer experimental autoimmune myasthenia gravis. (From Joynt, Clinical Neurology, 1997, Ch 54, p3)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Any autoimmune animal disease model used in the study of MYASTHENIA GRAVIS. Injection with purified neuromuscular junction acetylcholine receptor (AChR) (see RECEPTORS, CHOLINERGIC) components results in a myasthenic syndrome that has acute and chronic phases. The motor endplate pathology, loss of acetylcholine receptors, presence of circulating anti-AChR antibodies, and electrophysiologic changes make this condition virtually identical to human myasthenia gravis. Passive transfer of AChR antibodies or lymphocytes from afflicted animals to normals induces passive transfer experimental autoimmune myasthenia gravis. (From Joynt, Clinical Neurology, 1997, Ch 54, p3)

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

11 entry terms
  • Experimental Myasthenia
  • Experimental Myasthenia Gravis
  • Myasthenia Gravis, Autoimmune Experimental
  • Myasthenia Gravis, Autoimmune, Experimental
  • Myasthenia Gravis, Experimental Autoimmune
  • Experimental Myasthenias
  • Myasthenia Gravis, Experimental
  • Myasthenia, Experimental
  • Myasthenias, Experimental
  • Experimental Autoimmune Myasthenia Gravis, Passive Transfer
  • Passive Transfer Experimental Autoimmune Myasthenia Gravis

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2005 (2000)

MeSH Record

Previous Indexing

  • Autoimmune Diseases (1969-1999)
  • Myasthenia Gravis (1968-1999)

MeSH Hierarchy

Tree Numbers

  1. C10w.114.656w.300
  2. C10w.114.703.350
  3. C10w.668w.758w.725w.300
  4. C20w.111w.258.500w.300
  5. C20w.111w.258.625.350
  6. E05.598.500w.500.750

AMA Style

References

  1. National Library of Medicine. Autoimmune Experimental Myasthenia Gravis. Medical Subject Headings (MeSH). 2026. Unique ID D020720. http://id.nlm.nih.gov/mesh/2026/D020720
  2. Autoimmune Experimental Myasthenia Gravis. In: Wikidata. https://www.wikidata.org/wiki/Q55093027